Found 90 from Laval University 
Affinity DataIC50: 0.150nMAssay Description:Compound was tested for its ability to inhibit human embryonal kidney cell derived steroid sulfatase activity in transforming [3H]E1S (estrone sulfat...More data for this Ligand-Target Pair
Affinity DataIC50: 0.390nMAssay Description:Compound was tested for its ability to inhibit human embryonal kidney cell derived steroid sulfatase activity in transforming [3H]E1S (estrone sulfat...More data for this Ligand-Target Pair
Affinity DataIC50: 1.40nMAssay Description:Compound was tested for its ability to inhibit the transformation of [C14]-DHEAS to DHEA by steroid sulfatase derived from human embryonal kidney cel...More data for this Ligand-Target Pair
Affinity DataIC50: 1.60nMAssay Description:Inhibition of steroid sulfatase activity by the compound was determined in human embryonic kidney (HEK)-293 cells transfected with a sulfatase expres...More data for this Ligand-Target Pair
Affinity DataIC50: 2.10nMAssay Description:Compound was tested for its ability to inhibit human embryonal kidney cell derived steroid sulfatase activity in transforming [3H]E1S (estrone sulfat...More data for this Ligand-Target Pair
Affinity DataIC50: 2.40nMAssay Description:Inhibition of steroid sulfatase activity by the compound was determined in human embryonic kidney (HEK)-293 cells transfected with a sulfatase expres...More data for this Ligand-Target Pair
Affinity DataIC50: 4.10nMAssay Description:Compound was tested for its ability to inhibit the transformation of [C14]-DHEAS to DHEA by steroid sulfatase derived from human embryonal kidney cel...More data for this Ligand-Target Pair
Affinity DataIC50: 5.60nMAssay Description:Compound was tested for its ability to inhibit the transformation of [C14]-DHEAS to DHEA by steroid sulfatase derived from human embryonal kidney cel...More data for this Ligand-Target Pair
Affinity DataIC50: 8.30nMAssay Description:Compound was tested for its ability to inhibit human embryonal kidney cell derived steroid sulfatase activity in transforming [3H]E1S (estrone sulfat...More data for this Ligand-Target Pair
Affinity DataIC50: 12nMAssay Description:Steroid sulfatase activity was determined in human embryonic kidney (HEK)-293 cells transfected with a sulfatase expression vector (pCMV-sulfa) using...More data for this Ligand-Target Pair
Affinity DataIC50: 13nMAssay Description:Steroid sulfatase activity was determined in human embryonic kidney (HEK)-293 cells transfected with a sulfatase expression vector (pCMV-sulfa) using...More data for this Ligand-Target Pair
Affinity DataIC50: 14nMAssay Description:Compound was tested for its ability to inhibit the transformation of [C14]-DHEAS to DHEA by steroid sulfatase derived from human embryonal kidney cel...More data for this Ligand-Target Pair
Target17-beta-hydroxysteroid dehydrogenase type 3(Rattus norvegicus)
Laval University
Curated by ChEMBL
Laval University
Curated by ChEMBL
Affinity DataIC50: 14nMAssay Description:Inhibition of 17beta-HSD3 in rat testes microsomal fraction using [14C]-4-androstene-3,17-dione as substrate assessed as testosterone formation after...More data for this Ligand-Target Pair
Affinity DataIC50: 22nMAssay Description:Inhibition of steroid sulfatase activity of JEG-3 cellsMore data for this Ligand-Target Pair
Target17-beta-hydroxysteroid dehydrogenase type 3(Rattus norvegicus)
Laval University
Curated by ChEMBL
Laval University
Curated by ChEMBL
Affinity DataIC50: 22nMAssay Description:Inhibition of 17beta-HSD3 in rat testes microsomal fraction using [14C]-4-androstene-3,17-dione as substrate assessed as testosterone formation after...More data for this Ligand-Target Pair
Affinity DataIC50: 24nMAssay Description:Estrone sulfatase activity against homogenized human JEG-3 cells was determined by measuring the [3H]E1 obtained from [3H]E1SMore data for this Ligand-Target Pair
Affinity DataIC50: 24nMAssay Description:Inhibition of CYP3A4 (unknown origin) by fluorescence assayMore data for this Ligand-Target Pair
3D Structure (crystal)Affinity DataIC50: 24nMAssay Description:Inhibition of steroid sulfatase activity of JEG-3 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 25nMAssay Description:Inhibition of steroid sulfatase activity of JEG-3 cellsMore data for this Ligand-Target Pair
Target17-beta-hydroxysteroid dehydrogenase type 1(Homo sapiens (Human))
Laval University
Curated by ChEMBL
Laval University
Curated by ChEMBL
Affinity DataIC50: 27nMAssay Description:Inhibition of 17-beta HSD1 in human T47D cells assessed as transformation of [14C]E1 to [14C]E2 after 24 hrs by thin layer chromatographyMore data for this Ligand-Target Pair
Affinity DataIC50: 28nMAssay Description:Estrone sulfatase activity against homogenized human JEG-3 cells was determined by measuring the [3H]E1 obtained from [3H]E1SMore data for this Ligand-Target Pair
Affinity DataIC50: 28nMAssay Description:Inhibition of steroid sulfatase activity of JEG-3 cellsMore data for this Ligand-Target Pair
Target17-beta-hydroxysteroid dehydrogenase type 3(Homo sapiens (Human))
Laval University
Curated by ChEMBL
Laval University
Curated by ChEMBL
Affinity DataIC50: 57nMAssay Description:Inhibitory concentration against type-3 17-beta-HSD expressed in HEK293 cellsMore data for this Ligand-Target Pair
Target17-beta-hydroxysteroid dehydrogenase type 3(Rattus norvegicus)
Laval University
Curated by ChEMBL
Laval University
Curated by ChEMBL
Affinity DataIC50: 58nMAssay Description:Inhibition of 17beta-HSD3 in rat testes microsomal fraction using [14C]-4-androstene-3,17-dione as substrate assessed as testosterone formation after...More data for this Ligand-Target Pair
Target17-beta-hydroxysteroid dehydrogenase type 3(Homo sapiens (Human))
Laval University
Curated by ChEMBL
Laval University
Curated by ChEMBL
Affinity DataIC50: 60nMAssay Description:Inhibitory concentration against type-3 17-beta-HSD expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 62nMAssay Description:Inhibition of steroid sulfatase activity of JEG-3 cells by the compound at 20 uM, activity was determined by considering total labeled estrone ([3H]E...More data for this Ligand-Target Pair
Target17-beta-hydroxysteroid dehydrogenase type 3(Homo sapiens (Human))
Laval University
Curated by ChEMBL
Laval University
Curated by ChEMBL
Affinity DataIC50: 67nMAssay Description:Inhibitory concentration against type-3 17-beta-HSD expressed in HEK293 cellsMore data for this Ligand-Target Pair
Target17-beta-hydroxysteroid dehydrogenase type 1(Homo sapiens (Human))
Laval University
Curated by ChEMBL
Laval University
Curated by ChEMBL
Affinity DataIC50: 68nMAssay Description:Inhibition of 17-beta HSD1 in human T47D cells assessed as transformation of [14C]E1 to [14C]E2 after 24 hrs by thin layer chromatographyMore data for this Ligand-Target Pair
Target17-beta-hydroxysteroid dehydrogenase type 3(Homo sapiens (Human))
Laval University
Curated by ChEMBL
Laval University
Curated by ChEMBL
Affinity DataIC50: 73nMAssay Description:Inhibitory concentration against type-3 17-beta-HSD expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 80nMAssay Description:Estrone sulfatase activity against homogenized human JEG-3 cells was determined by measuring the [3H]E1 obtained from [3H]E1SMore data for this Ligand-Target Pair
Affinity DataIC50: 80nMAssay Description:Inhibition of steroid sulfatase activity of JEG-3 cellsMore data for this Ligand-Target Pair
Target17-beta-hydroxysteroid dehydrogenase type 3(Homo sapiens (Human))
Laval University
Curated by ChEMBL
Laval University
Curated by ChEMBL
Affinity DataIC50: 81nMAssay Description:Inhibitory concentration against type-3 17-beta-HSD expressed in HEK293 cellsMore data for this Ligand-Target Pair
Target17-beta-hydroxysteroid dehydrogenase type 3(Homo sapiens (Human))
Laval University
Curated by ChEMBL
Laval University
Curated by ChEMBL
Affinity DataIC50: 87nMAssay Description:Inhibitory concentration against type-3 17-beta-HSD expressed in HEK293 cellsMore data for this Ligand-Target Pair
Target17-beta-hydroxysteroid dehydrogenase type 3(Homo sapiens (Human))
Laval University
Curated by ChEMBL
Laval University
Curated by ChEMBL
Affinity DataIC50: 97nMAssay Description:Inhibitory concentration against type-3 17-beta-HSD expressed in HEK293 cellsMore data for this Ligand-Target Pair
Target17-beta-hydroxysteroid dehydrogenase type 1(Homo sapiens (Human))
Laval University
Curated by ChEMBL
Laval University
Curated by ChEMBL
Affinity DataIC50: 97nMAssay Description:Inhibition of 17-beta HSD1 in human T47D cellsMore data for this Ligand-Target Pair
Target17-beta-hydroxysteroid dehydrogenase type 3(Homo sapiens (Human))
Laval University
Curated by ChEMBL
Laval University
Curated by ChEMBL
Affinity DataIC50: 99nMAssay Description:Inhibitory concentration against type-3 17-beta-HSD expressed in HEK293 cellsMore data for this Ligand-Target Pair
Target17-beta-hydroxysteroid dehydrogenase type 3(Homo sapiens (Human))
Laval University
Curated by ChEMBL
Laval University
Curated by ChEMBL
Affinity DataIC50: 100nMAssay Description:Inhibitory concentration against type-3 17-beta-HSD expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 110nMAssay Description:Estrone sulfatase activity against homogenized human JEG-3 cells was determined by measuring the [3H]E1 obtained from [3H]E1SMore data for this Ligand-Target Pair
Affinity DataIC50: 110nMAssay Description:Inhibition of steroid sulfatase activity of JEG-3 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 110nMAssay Description:Estrone sulfatase activity against homogenized human JEG-3 cells was determined by measuring the [3H]E1 obtained from [3H]E1SMore data for this Ligand-Target Pair
Affinity DataIC50: 110nMAssay Description:Inhibition of steroid sulfatase activity of JEG-3 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 120nMAssay Description:Inhibition of steroid sulfatase activity of JEG-3 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 130nMAssay Description:Inhibition of steroid sulfatase activity of JEG-3 cellsMore data for this Ligand-Target Pair
Target17-beta-hydroxysteroid dehydrogenase type 3(Homo sapiens (Human))
Laval University
Curated by ChEMBL
Laval University
Curated by ChEMBL
Affinity DataIC50: 147nMAssay Description:Inhibitory concentration against type-3 17-beta-HSD expressed in HEK293 cellsMore data for this Ligand-Target Pair
Target17-beta-hydroxysteroid dehydrogenase type 1(Homo sapiens (Human))
Laval University
Curated by ChEMBL
Laval University
Curated by ChEMBL
Affinity DataIC50: 153nMAssay Description:Inhibition of 17-beta HSD1 in human T47D cells assessed as transformation of [14C]E1 to [14C]E2 after 24 hrs by thin layer chromatographyMore data for this Ligand-Target Pair
Target17-beta-hydroxysteroid dehydrogenase type 1(Homo sapiens (Human))
Laval University
Curated by ChEMBL
Laval University
Curated by ChEMBL
Affinity DataIC50: 172nMAssay Description:Inhibition of 17-beta HSD1 in human T47D cells assessed as transformation of [14C]E1 to [14C]E2 after 24 hrs by thin layer chromatographyMore data for this Ligand-Target Pair
Affinity DataIC50: 220nMAssay Description:Steroid sulfatase activity was determined in human embryonic kidney (HEK)-293 cells transfected with a sulfatase expression vector (pCMV-sulfa) using...More data for this Ligand-Target Pair
Affinity DataIC50: 230nMAssay Description:Compound was tested for its ability to inhibit human embryonal kidney cell derived steroid sulfatase activity in transforming [3H]E1S (estrone sulfat...More data for this Ligand-Target Pair
Affinity DataIC50: 310nMAssay Description:Inhibition of steroid sulfatase activity of JEG-3 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 310nMAssay Description:Estrone sulfatase activity against homogenized human JEG-3 cells was determined by measuring the [3H]E1 obtained from [3H]E1SMore data for this Ligand-Target Pair
